The high-precision control bioreactor is equipped with 1 MFC, featuring higher control accuracy and greater stability.
| Model | BIOR-M1P | BIOR-M2P | BIOR-M3P | BIOR-M5P | BIOR-M7P | BIOR-M10P | BIOR-M15P | |
| Independent Control Tower | Housing Material | Carbon steel, plastic powder coating | ||||||
| Display | 15.6″ color touch screen | |||||||
| Controller | Siemens S series PLC, MCGS HMI | |||||||
| Integrated Pump | 4 Matson Marlow 114 variable-speed peristaltic pumps | |||||||
| Flow Meter | 2 rotameters + 1 MFC | |||||||
| Communication | USB [software upgrade, data copy and export], Industrial Ethernet, WiFi, 1 × Analog Input 4 to 20 mA | |||||||
| Interface | 1 × pH sensor cable; 1 × DO sensor cable; 2 × stirring motor control wires; 1 × temperature sensor interface; 1 × foam sensor cable; 1 × heating blanket control wire interface; 1 × main power interface | |||||||
| Water Interface | 6 × hose barb fitting (inlet/outlet for exhaust condenser, cooling finger, chilled water) | |||||||
| Air Interface | 3 × hose barb fitting (2 × gas supply interface, 1 × gas outlet) | |||||||
| Power Supply | 220 V (±10%), 50 Hz, single phase | |||||||
| Rated Power | Max. 1.5 kW | |||||||
| External Size (W×D×H) | 435×360×730 mm | |||||||
| Net Weight | Approx. 40 kg (depending on configuration) | |||||||
| Agitation Control | Motor | Maintenance-free, low noise servo motor | ||||||
| Speed Range | 5 – 1000 rpm | |||||||
| Speed Accuracy | ± 0.5% | |||||||
| Rated Power | Max. 750 W | |||||||
| Gas Control | Gas Source | Air, O2 | ||||||
| Control Method | 1 × MFC, 2 × rotameters, 1 × solenoid valve | |||||||
| Gas Inlet | Ring sparger | |||||||
| Flow Range | Sparger Air: rotameter 3 – 30 L/min, MFC max. 20 SLPM Sparger O2: rotameter 0.5-8 L/min | |||||||
| Flow Accuracy | Rotameter accuracy: ± 4%, MFC accuracy: ± 1% | |||||||
| Temperature Control | Control Method | Robust PID algorithm | ||||||
| Heating Method | Heating blanket | |||||||
| Heating Power | Max. 500 W, each vessel | |||||||
| Cooling Method | Tap water or circulating cooling | |||||||
| Sensor | Pt100 RTD (JUMO, German) | |||||||
| Measurement Range | 0~150.0 °C | |||||||
| Measurement Accuracy | ± 0.1 °C | |||||||
| Control Range | 8.0 °C above coolant to 40.0 °C above ambient (0 – 65.0 °C absolute) | |||||||
| Control Accuracy | ± 0.2 °C | |||||||
| PH Control | Control Method | · Robust PID algorithm · Cascade control with peristaltic pumps by adding acid and alkali | ||||||
| Sensor | Hamilton Sterilizable Gel-filled pH electrode | |||||||
| Measurement Range | 2.00~12.00 | |||||||
| Measurement Accuracy | 0.01 | |||||||
| Control Accuracy | ± 0.05 | |||||||
| DO Control | Control Method | · Robust PID algorithm · Cascade control with different parameters (agitation, gas flow and pump) | ||||||
| Sensor | Hamilton Sterilizable polarographic DO electrode | |||||||
| Measurement Range | 0.0~150.0% | |||||||
| Measurement Accuracy | 0.1% | |||||||
| Control Accuracy | ± 3% | |||||||
| Foam Control | Control Method | · Cascade control with peristaltic pump by adding antifoam (defoamer) · Mechanical defoaming blade | ||||||
| Model | BIOR-M1P | BIOR-M2P | BIOR-M3P | BIOR-M5P | BIOR-M7P | BIOR-M10P | BIOR-M15P | |
| Glass Vessel | Type | Single-wall round-bottom cylindrical vessel, available for electric blanket | ||||||
| Total Volume | 1 L | 2 L | 3 L | 5 L | 7 L | 10 L | 15 L | |
| Max. Working Volume | 0.75 L | 1.5 L | 2.25 L | 3.75 L | 5.25 L | 7.5 L | 11.25 L | |
| Min. Working Volume | 0.25 L | 0.5 L | 0.75 L | 1.25 L | 1.75 L | 2.5 L | 3.75 L | |
| Material (Wetted Part) | · Glass vessel material: Boro 3.3 high borosilicate glass | |||||||
| · Vessel cover and inner parts: SUS 316 L | ||||||||
| · Seal: EPDM and Silicon | ||||||||
| Surface Treatment | · Inner surface: electrolytic polishing, Ra ＜0.4 μm | |||||||
| · Outer surface: Ra ＜0.6 μm | ||||||||
| Pressure Design | Working pressure: 0~1 bar @ 150°C Autoclavable | |||||||
| Height to Diameter Ratio [H: D] | Approx. 2:1 | |||||||
| Vessel Dimensions | Refer to “Table A” | |||||||
| Vessel Weight (Excluding Motor) | 8 kg | 9 kg | 10 kg | 12 kg | 13.5 kg | 15 kg | 18 kg | |
| Vessel Lid Interface | 1 × Agitator flange for top mechanical stirring; 1 × Flame inoculation port; | |||||||
| 2 × Baffle port, including cooling coil; 1 × Gas inlet port for ring sparger; | ||||||||
| 1 × Exhaust port, including water-cooled exhaust condenser; 1 × PH sensor port; | ||||||||
| 1 × DO sensor port; 1 × PT100 temperature sensor port; 1 × Foam sensor port; | ||||||||
| 1 × Sampling port N × Feeding port; | ||||||||
| Impellers | · < 5 L: 2 layers, top: foam breaker, bottom: 6-blade Rushton impeller | |||||||
| · ≥ 5 L: 3 layers, top: foam breaker; middle: 4-blade pitched impeller; bottom: 6-blade Rushton impeller | ||||||||
| · Detachable, height adjustable | ||||||||
| Baffles | · <3 L: 2 removable baffles · ≥ 3 L: 4 removable baffles | |||||||
Table A:
| Dimension | |||||||
| Vessel Volume | 1 L | 2 L | 3 L | 5 L | 7 L | 10 L | 15 L |
| a (mm) | 450 | 471 | 567 | 622 | 712 | 753 | 851 |
| b (mm) | 430 | 450 | 492 | 546 | 636 | 641 | 738 |
| c (mm) | 227 | 214 | 292 | 347 | 437 | 442 | 484 |
| d (mm) | 170 | 190 | 230 | 280 | 370 | 360 | 450 |
| e (mm) | Ø90 | Ø110 | Ø130 | Ø150 | Ø160 | Ø185 | Ø203 |
| f (mm) | 180 | 190 | 190 | 212 | 212 | 248 | 270 |
| Sterilization Requirement | |||||||
| Minimum Size (mm) | Ø220×450 | Ø230×470 | Ø230×500 | Ø265×550 | Ø265×640 | Ø300×645 | Ø335×740 |
| Recommended Size (mm) | Ø280×500 | Ø280×500 | Ø280×555 | Ø300×600 | Ø300×700 | Ø350×700 | Ø380×800 |
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