Bioreactor, BIOR-M Series

Bioreactor, BIOR-M Series

This bioreactor offers you a fast and convenient standardized microbial culture solution, with simple operation and quick assembly. It is suitable for suspension and adherent cell culture processes, as well as for PD scale to full cGMP production workflows.

  • Model : BIOR-M1; BIOR-M2; BIOR-M3; BIOR-M5L; BIOR-M7; BIOR-M10; BIOR-M15
  • Total Volume (L): 1/2/3/5/7/10/15
  • Flow Meter: 2 rotameters
  • Gas Source: Air, O2
  • Material (Vessel): Borosilicate 3.3 glass
  • Temperature Range: 0~150.0 °C
  • PH Range: 2.00~12.00
  • DO Range: 0.0~150.0%

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Advantage:

  • Cost-effective and Non-redundant: Standardized solution for microbial cultivation.
  • Intuitive Interface: 10.1-inch touch screen with graphical design language, making operation no longer complicated.
  • Quick and Easy Installation: Small footprint and no tools are required for installation.
  • Mature Vessel Manufacturing Process: All components are located on the vessel lid, easy to disassemble, maintain and clean.
  • Reliable Performance and Precise Control: Leading international brands core hardware ensures stability.
  • Versatile Total Volumes: 7 options from 1 L to 15 L for diverse scales.
  • Powerful Software Functions: Full control via feedback, time, conditions, scripts, etc.
  • Easy Sterilization: The separation of the base, vessel body and stirring motor enables a lightweight design, making it easier for experimenters to transfer it to the sterilizer.
  • Remote Communication: Wired and wireless LAN for remote monitoring and control.
  • Ready to Use after Installation: The complete kit includes everything needed for the application, pre-configured, and ready to use, without the need to purchase additional accessories.
  • Flexible Customization: Extensive upgrades and bespoke solutions for special needs.

Bioreactor Specifications:  

Model BROR-M1 BROR-M2 BROR-M3 BROR-M5L BROR-M7 BROR-M10 BROR-M15
Independent Control Tower Housing Material Carbon steel, plastic powder coating
Display 10.1″ color touch screen
Controller Siemens S series PLC, MCGS HMI
Integrated Pump 4 fixed-speed fast-loading peristaltic pumps
Flow Meter 2 rotameters
Communication USB (software upgrade, data copy and export), Industrial Ethernet, WiFi
Interface 1 x pH sensor cable;          1 x DO sensor cable;       2 x stirring motor control wires;
1 x temperature sensor interface;           1 x foam sensor cable;
1 x heating base control wire interface;   1 x main power interface
Water Interface 6 × hose barb fitting (inlet/outlet for exhaust condenser, base jacket and chilled water)
Air Interface 3 × hose barb fitting (2 x gas supply interface, 1 x gas outlet)
Power Supply 220V (±10%), 50Hz, single phase
Rated Power 400 W 600 W 800 W 900 W 900 W 1500 W 1500 W
External Size (WxDxH) 360×500×720mm
Net Weight Approx. 40 Kg (depending on configuration)
Agitation Control Motor Maintenance-free, low noise servo motor
Speed Range 5 – 1000 rpm
Speed Accuracy ± 0.5%
Rated Power 200 W 400 W 400 W 400 W 400 W 750 W 750 W
Gas Control Gas Source Air, O2
Control Method Air: rotameter;   O2: rotameter + solenoid valve
Gas Inlet Ring sparger
Flow Range Sparger – Air: Max. design 2 vvm;      Sparger – O2: Max. design 1 vvm
Flow Accuracy ± 4%
Temperature Control Control Method Robust PID algorithm
Heating Method Closed loop system with circulating jacket, bottom electric hot plate
Heating Power 80 W 80 W 200 W 330 W 330 W 550 W 550 W
Cooling Method Tap water or circulating cooling water
Sensor Pt100 RTD (JUMO, German)
Measurement Range 0~150.0°C
Measurement Accuracy ± 0.1°C
Control Range 8.0 °C above coolant to 40.0 °C above ambient (0-65.0 °C absolute)
Control Accuracy ± 0.2°C
PH Control Control Method · Robust PID algorithm  · Cascade control with peristaltic pumps by adding acid and alkali
Sensor Hamilton Sterilizable Gel-filled pH electrode
Measurement Range 2.00~12.00
Measurement Accuracy 0.01
Control Accuracy ± 0.05
DO Control Control Method · Robust PID algorithm  · Cascade control with different parameters (agitation, gas flow and pump)
Sensor Hamilton Sterilizable polarographic DO electrode
Measurement Range 0.0~150.0%
Measurement Accuracy 0.10%
Control Accuracy ± 3%
Foam Control Control Method · Cascade control with peristaltic pump by adding antifoam (defoamer)      · Mechanical defoaming blade

Bioreactor Specifications (Glass Vessel) : 

Model BIOR-M1 BIOR-M2 BIOR-M3 BIOR-M5L BIOR-M7 BIOR-M10 BIOR-M15
Glass Vessel Type Single-wall flat-bottom cylindrical vessel, available for heating base
Total Volume 1 L 2 L 3 L 5 L 7 L 10 L 15 L
Max. Working Volume 0.75 L 1.5 L 2.25 L 3.75 L 5.25 L 7.5 L 11.25 L
Min. Working Volume 0.25 L 0.5 L 0.75 L 1.25 L 1.75 L 2.5 L 3.75 L
Material (Wetted Part) · Glass vessel material: Borosilicate 3.3 glass
· Vessel cover and inner parts: SUS 316L
· Seal: EPDM and Silicon
Surface Treatment · Inner surface: electrolytic polishing, Ra ＜0.4 μm
· Outer surface: Ra ＜0.6 μm
Pressure Design Working pressure: 0~1 bar @ 150°C Autoclavable
Height to Diameter Ratio [H: D] Approx. 2:1
Vessel  Dimensions Refer to “Table A”
Vessel Weight (Excluding Motor) 8 kg 10 kg 11 kg 13 kg 15 kg 17 kg 20 kg
Base Weight (With Bottle Holder) 8 kg 8 kg 10 kg 10 kg 10 kg 15 kg 15 kg
Vessel Lid Interface 1 × Agitator flange for top mechanical stirring;      1 × Flame inoculation port;
2 × Baffle port, including cooling coil;      1 × Gas inlet port for ring sparger;
1 × Exhaust port, including water-cooled exhaust condenser;      1 × PH sensor port;
1 × DO sensor port;      1 × PT100 temperature sensor port;      1 × Foam sensor port;
1 × Sampling port;      N × Feeding  port;
Impellers · < 5 L: 2 layers, top: foam breaker, bottom: 6-blade Rushton impeller
· ≥ 5 L: 3 layers, top: foam breaker; middle: 4-blade pitched impeller; bottom: 6-blade Rushton impeller
Baffles · <3 L:  2 removable baffles       · ≥ 3 L: 4 removable baffles

Table A: 

Dimension
Vessel Volume 1 L 2 L 3 L 5 L 7 L 10 L 15 L
a (mm) 448 540 637 656 736 840 888
b (mm) 360 430 470 486 522 616 700
c (mm) 205 254 270 286 368 430 470
d (mm) 170 230 230 240 315 380 420
e (mm) Ø90 Ø110 Ø140 Ø170 Ø170 Ø185 Ø216
f (mm) 156 156 187 220 220 240 275
g (mm) 210 210 248 267 267 300 340
Sterilization Requirement
Minimum Size (mm) Ø195×365 Ø195×450 Ø230×475 Ø270×500 Ø270×590 Ø275×645 Ø320×710
Recommended Size (mm) Ø260×400 Ø260×500 Ø300×555 Ø300×555 Ø330×650 Ø330×650 Ø370×750

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Scitek Global Co., Ltd is a professional manufacturer of laboratory and medical equipment, certified by ISO9001, ISO14001 and ISO45001. Since our inception, we have been committed to providing high-quality laboratory and medical products to our customers worldwide.

Our products cover a wide range of laboratory needs, including, but not limited to, laboratory ultra-low clod freezer, laboratory incubators, sterilizers, centrifuges, freeze dryer, and many other types of equipment.

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Factory: Liancheng Manufacturing Town, No. 19 Huanghe Street, Jinan City, Shandong Province, China

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